Circulating oxysterols and prognosis among women with a breast cancer diagnosis: results from the MARIE patient cohort.
Nina Sophia DeckerTheron JohnsonJohannes A VeyCharlotte Le CornetSabine BehrensNadia ObiRudolf KaaksJenny Chang-ClaudeRenée Turzanski FortnerPublished in: BMC medicine (2023)
We provide first evidence on a range of circulating oxysterols and mortality following a breast cancer diagnosis, contributing to a better understanding of associations between different pathways of cholesterol metabolism and prognosis in women with a breast cancer diagnosis. The findings of this study suggest circulating oxysterols may be associated with cardiovascular mortality among women diagnosed with breast cancer. Further studies are needed to evaluate these oxysterols as potential markers of risk for cardiovascular mortality among women with a breast cancer diagnosis as well as their clinical potential.