Eosinophilic gastroenteritis and graft-versus-host disease induced by transmission of Norovirus with fecal microbiota transplant.

Jarosław BilińskiKarol LisAgnieszka TomaszewskaAleksandra PechcinskaPawel GrzesiowskiTomasz DzieciatkowskiAlicja WalesiakBeata GierejBogna Ziarkiewicz-WróblewskaMartyna TyszkaPiotr KacprzykLidia ChmielewskaAnna Waszczuk-GajdaWieslaw Wiktor-JedrzejczakGrzegorz W Basak

Published in: Transplant infectious disease : an official journal of the Transplantation Society (2021)

Fecal microbiota transplantation (FMT) was performed to decolonize gastrointestinal tract from antibiotic-resistant bacteria before allogeneic hematopoietic cells transplantation (alloHCT). AlloHCT was complicated by norovirus gastroenteritis, acute graft-versus-host disease, and eosinophilic pancolitis. Norovirus was identified in samples from FMT material. Symptoms resolved after steroids course and second norovirus-free FMT from another donor.

Keyphrases

bone marrow
induced apoptosis
stem cell transplantation
liver failure
cell therapy
oxidative stress
stem cells
respiratory failure
intensive care unit
mesenchymal stem cells
drug induced
signaling pathway
physical activity
acute respiratory distress syndrome