ADGRL1 is a glucose receptor involved in mediating energy and glucose homeostasis.
Kavaljit H ChhabraSiresha BathinaTumininu S FaniyanDennis J SamuelMuhammad Ummear RazaLeticia Maria de Souza CordeiroGonzalo Viana Di PriscoBrady K AtwoodJorge RoblesLauren BainbridgeAutumn DavisPublished in: Diabetologia (2023)
Altogether, our findings demonstrate that ADGRL1 binds glucose and is involved in energy as well as glucose homeostasis in a sex-dependent manner. Targeting ADGRL1 may introduce a new class of drugs for the treatment of type 2 diabetes and obesity.