In Vitro Evaluation of the Neuroprotective Effect of Panax notoginseng Saponins by Activating the EGFR/PI3K/AKT Pathway.

Shuang WuTiantian YangKai CenYihuai ZouXiaowei ShiDongrui ZhouYonghong Gao Limin Chai Yizhou ZhaoYikun SunLingqun Zhu

Published in: Evidence-based complementary and alternative medicine : eCAM (2020)

These findings indicate that PNS enhanced neuroprotective effects by activating the EGFR/PI3K/AKT pathway and elevating phosphorylation levels in OGD SH-SY5Y cells.

Keyphrases

small cell lung cancer
epidermal growth factor receptor
signaling pathway
induced apoptosis
tyrosine kinase
cell cycle arrest
endoplasmic reticulum stress
pi k akt
oxidative stress
cell death
protein kinase
brain injury