A decrease in serum 1,25(OH) 2 D after elective hip replacement and during bone healing is associated with changes in serum iron and plasma FGF23.

D, plasma intact to C-terminal FGF23 ratio, and serum iron on the first day as well as 7 weeks after surgery could inspire future studies to determine whether and how calcitriol deficiency should be corrected, especially in fracture cases.