Hydropyridylation of Olefins by Intramolecular Minisci Reaction.

Published in: Organic letters (2017)

An unprecedented cheap, mild and easy methodology for an intramolecular Minisci reaction based on a hydrogen atom transfer (HAT) initiated hydrofunctionalization of olefins was developed. The method is suitable for the construction of unusual dihydropyrano-pyridine and 1,2,3,4-tetrahydronaphthiridine structures and, unlike most similar reactions, does not require exclusion of air from the reaction medium.

Keyphrases

electron transfer
high resolution
molecular dynamics
energy transfer