PlGF and sFlt-1 levels in patients with non-transfusion-dependent thalassemia: Correlations with markers of iron burden and endothelial dysfunction.

Charikleia KelaidiAntonis KattamisFilia ApostolakouChristos PoziopoulosChristina LazaropoulouPolyxeni DelaportaIno KanavakiIoannis Papassotiriou

Published in: European journal of haematology (2018)

In this study, we demonstrated an association between increased PlGF and iron overload and the degree of tissue hypoxia in patients with NTDT. High vWF:antigen expressing endothelial damage may be associated with specific NTDT comorbidities.

Keyphrases

endothelial cells
sickle cell disease
oxidative stress
iron deficiency
cardiac surgery
acute kidney injury