Impact of Exacerbation History on Dupilumab Efficacy in Children with Uncontrolled Moderate-to-Severe Asthma: LIBERTY ASTHMA VOYAGE Study.

Theresa W GuilbertAlberto TolcachierAlessandro G FiocchiConstance H KatelarisWanda PhipatanakulPhilippe BeginInés de MirArman AltincatalRebecca GallOlivier LedanoisAmr RadwanJuby A Jacob-NaraYamo DenizPaul J Rowe

Published in: Journal of asthma and allergy (2024)

In children with uncontrolled, moderate-to-severe asthma with a type 2 phenotype, dupilumab consistently reduced the risk of asthma exacerbations, improved lung function, and reduced ACQ-7-IA scores, regardless of exacerbation history.

Keyphrases

chronic obstructive pulmonary disease
lung function
cystic fibrosis
atopic dermatitis
young adults
high intensity
air pollution
acute respiratory distress syndrome