Suppression of Heart Failure With PAR1 Pepducin Technology in a Pressure Overload Model in Mice.
Elizabeth K FletcherNjabulo NgwenyamaNga NguyenSusan E TurnerLidija CovicPilar AlcaideAthan KuliopulosPublished in: Circulation. Heart failure (2023)
The PZ-128 pepducin is highly effective in protecting against cardiac inflammation, fibrosis, and loss of left ventricle function in a mouse model.