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Subsecond lung cancer detection within a heterogeneous background of normal and benign tissue using single-point Raman spectroscopy.

Frédérick DallaireFrédérick DallaireTrang TranRajeev YadavKelly AubertinEric GoudiePhilippe RomeoChristopher KentCharles LeducMoishe Liberman
Published in: Journal of biomedical optics (2023)
This proof of concept demonstrates fingerprint Raman spectroscopy is a promising tool for the detection of lung cancer during diagnostic procedures and can capture biomolecular changes associated with the presence of cancer among a complex heterogeneous background within less than 1 s.
Keyphrases
  • raman spectroscopy
  • loop mediated isothermal amplification
  • real time pcr
  • label free
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  • young adults
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