Performance of repeat cytology with reflex ThyroSeq genomic classifier for indeterminant thyroid cytology.
Christopher J O'ConorRajesh C DashClaudia K JonesXiaoyin 'Sara' JiangPublished in: Cancer cytopathology (2022)
In the majority of patients, repeat FNAB for AUS/FLUS did not preclude subsequent molecular ancillary testing because of the high rate of indeterminant results on repeat biopsy. The diagnostic performance of the testing algorithm reported here was very similar to other reports using either repeat biopsy or molecular testing alone. Ultimately, the algorithm of performing molecular testing on repeat indeterminant nodules increased the number of biopsies performed and lengthened the time to definitive risk stratification without a disproportionate decrease in the use of molecular testing or an appreciable improvement in diagnostic performance.
Keyphrases
- fine needle aspiration
- ultrasound guided
- end stage renal disease
- machine learning
- high grade
- single molecule
- deep learning
- chronic kidney disease
- ejection fraction
- peritoneal dialysis
- emergency department
- prognostic factors
- gene expression
- radiation therapy
- dna methylation
- patient reported outcomes
- rectal cancer
- neural network
- adverse drug