Significance of CEBPE Gene Promoter Polymorphism (Rs2239630 G > A ) Assessment in Childhood B-cell Acute Lymphoblastic Leukemia.

Salah ArefMohamed El-GhonemyHendawy ShimaaAhmad DarwishSuzy AbdelmaboodNada Khaled

Published in: Journal of pediatric hematology/oncology (2023)

CEBPE gene promoter polymorphism (rs2239630 G > A ) AA is frequently associated with B-ALL; and has the worst overall survival among the 3 genotypes, followed by the GA and GG genotypes ( P < 0.001).

Keyphrases

acute lymphoblastic leukemia
dna methylation
genome wide
copy number
transcription factor
gene expression
pet ct
genome wide identification
allogeneic hematopoietic stem cell transplantation
early life
young adults
acute myeloid leukemia
childhood cancer