Dynamic nanopore long-read sequencing analysis of HIV-1 splicing events during the early steps of infection.

Nam Nguyen QuangSophie GoudeyEmmanuel SégéralAmmara MohammadSophie LemoineCorinne BlugeonMargaux VersapuechJean-Christophe PaillartClarisse Berlioz-TorrentStéphane EmilianiSarah Gallois-Montbrun

Published in: Retrovirology (2020)

ONT sequencing is a convenient and reliable strategy that enabled us to grasp the dynamic of the early splicing events modulating the viral RNA landscape in HIV-1 infected cells.

Keyphrases

hiv infected
antiretroviral therapy
single cell
induced apoptosis
human immunodeficiency virus
single molecule
hiv positive
hiv aids
hepatitis c virus
cell cycle arrest
hiv testing
south africa