Two classic mutations in the linker-helix IIL45 and segment IIS6 of Apolygus lucorum sodium channel confer pyrethroid resistance.
Likui WangLianyun LinHao WangWenbo DuanFen LiKun ZhangPeng CaoZhiguang YuchiShaoying WuPublished in: Pest management science (2020)
Our results illustrate the distinct effect of mutations on pyrethroids. It is predicted with computer modeling that these mutations allosterically affect pyrethroid binding. © 2020 Society of Chemical Industry.