Interrupting the nitrosative stress fuels tumor-specific cytotoxic T lymphocytes in pancreatic cancer.
Francesco De SanctisAlessia LamolinaraFederico BoschiChiara MusiuSimone CaligolaRosalinda TrovatoAlessandra FioreCristina FrusteriCristina AnselmiOrnella PoffeTiziana CestariStefania CanèSilvia SartorisRosalba GiugnoGiulia Del RosarioBarbara ZappacostaFrancesco Del PizzoMatteo FassanErica DugnaniLorenzo PiemontiEmanuela BottaniIlaria DecimoSalvatore PaiellaRoberto SalviaRita Teresa LawlorVincenzo CorboYoungkyu ParkDavid A TuvesonClaudio BassiAldo ScarpaManuela IezziStefano UgelVincenzo BrontePublished in: Journal for immunotherapy of cancer (2022)
Tumor microenvironment reprogramming by ablating aberrant RNS production bypasses the current limits of immunotherapy in PDAC by overcoming immune resistance.
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