Platelet-Derived Mitochondria Attenuate 5-FU-Induced Injury to Bone-Associated Mesenchymal Stem Cells.

Yutong Chen Zhixin Liu Ning An Jing Zhang Weicheng Meng Wenting Wang Xiaoshuang Wu Xingbin Hu Yaozhen Chen Wen Yin

Published in: Stem cells international (2023)

. Meanwhile, platelet-derived mitochondria could attenuate the 5-FU-induced injury to BA-MSCs, which provides future research directions for exploring the treatment strategies for chemotherapy-injured BA-MSCs and establishes a research basis for related fields.

Keyphrases

mesenchymal stem cells
umbilical cord
high glucose
diabetic rats
cell death
drug induced
bone marrow
reactive oxygen species
oxidative stress
endoplasmic reticulum
endothelial cells
stem cells
radiation therapy
body composition
bone loss
chemotherapy induced