Vascular and metabolic effects of metformin added to insulin therapy in patients with type 1 diabetes: A systematic review and meta-analysis.

Ying-Shan LiuChu-Na ChenZhen-Guo ChenYu PengXiao-Pu LinLing-Ling Xu

Published in: Diabetes/metabolism research and reviews (2020)

Metformin with insulin has the potential to retard the progression of atherosclerosis and provides better metabolic control in patients with T1DM, and thus, providing a potential therapeutic strategy for patients with T1DM on reducing CVD risks.

Keyphrases

glycemic control
type diabetes
human health
cardiovascular disease
adipose tissue
insulin resistance
metabolic syndrome
mesenchymal stem cells
skeletal muscle
cell therapy