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FOXE1 polymorphism rs965513 predisposes to thyroid cancer in a European cohort.

Patrick W OwensTerri Patricia McVeighNicola MillerCarole GuerinFrederic SebagDenis QuillMarcia BellMichael J KerinAoife J Lowery
Published in: Endocrine oncology (Bristol, England) (2021)
polymorphism is a low penetrance variant associated with DTC susceptibility in this cohort. The minor allele was identified among patients with thyroid cancer significantly more frequently than controls. An allele dosage effect was observed, with rare homozygous genotypes conferring greater risk than heterozygotes.
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