Effect of exosomes from adipose-derived stem cells on the apoptosis of Schwann cells in peripheral nerve injury.

Cai-Yue LiuGang YinYi-Dan SunYao-Fa LinZheng XieArthur W EnglishQing-Feng LiHao-Dong Lin

Published in: CNS neuroscience & therapeutics (2019)

Our results present a novel exosome-mediated mechanism for ADSC-SC cross talk that reduces the apoptosis and promotes the proliferation of SCs and may have therapeutic potential in the future.

Keyphrases

peripheral nerve
cell cycle arrest
cell death
endoplasmic reticulum stress
induced apoptosis
pi k akt
oxidative stress
signaling pathway
mesenchymal stem cells
stem cells
current status
cell proliferation
wound healing