Comparison of transcriptional responses between pathogenic and nonpathogenic hantavirus infections in Syrian hamsters using NanoString.
Rebecca L BrocatoLouis A AltamuraMichael D BarreraCasey C PerleyCandace D BlancettTimothy D MinogueJay W HooperPublished in: PLoS neglected tropical diseases (2021)
Delayed activation of type I interferon responses in ANDV-infected hamsters represents a potential mechanism that ANDV uses to subvert host immune responses and enhance disease. This is the first genome-wide analysis of hantavirus-infected hamsters and provides insight into potential avenues for therapeutics to hantavirus disease.