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Delving into Molecular Pathways: Analyzing the Mechanisms of Action of Monoclonal Antibodies Integrated in IMGT/mAb-DB for Myasthenia Gravis.

Rebecca GolfinopoulouVéronique GiudicelliTaciana MansoSofia Kossida
Published in: Vaccines (2023)
The MOA of each new mAb needs to be considered in association with the immunopathogenesis of each of the subtypes of MG in order to integrate the new mAbs as a viable and safe option in the therapy decision process. In IMGT/mAb-DB, mAbs for MG are characterized by their sequence, domains, and chains, and their MOA is described.
Keyphrases
  • myasthenia gravis
  • monoclonal antibody
  • single molecule
  • amino acid