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Generating Rho-0 Cells Using Mesenchymal Stem Cell Lines.

Mercedes Fernández-MorenoTamara Hermida-GómezM Esther GallardoAndrea Dalmao-FernándezIgnacio Rego-PérezRafael GaresseFrancisco Javier Blanco
Published in: PloS one (2016)
Among the drugs and conditions tested, the use of d4t was the best option for producing Rho-0 cells from hMSCs. Rho-0 cells are useful for studying the role of mitochondria in hMSC differentiation.
Keyphrases
  • induced apoptosis
  • cell cycle arrest
  • mesenchymal stem cells
  • protein kinase
  • cell death
  • endoplasmic reticulum stress
  • smooth muscle
  • signaling pathway
  • oxidative stress
  • stem cells
  • pi k akt
  • cell therapy
  • drug induced