Novel TCF21 high pericyte subpopulation promotes colorectal cancer metastasis by remodelling perivascular matrix.
Xiaobo LiJinghua PanTongzheng LiuWenqian YinQun MiaoZhan ZhaoYufeng GaoWei ZhengHang LiRong DengDandan HuangShenghui QiuYiran ZhangQi QiLijuan DengMaohua HuangPatrick Ming-Kuen TangYihai CaoMinfeng ChenWencai YeDong-Mei ZhangPublished in: Gut (2022)
This study uncovers a previously unidentified role of TPCs in haematogenous metastasis and provides a potential diagnostic marker and therapeutic target for CRC metastasis.