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Synchronous oral squamous cell carcinoma and a lymphoproliferative disorder in an adult: a challenge in diagnosis and management.

Troy Van der GroenRaymond Patrick ShupakRoderick Y Kim
Published in: BMJ case reports (2022)
Synchronous primary malignancies present challenges in diagnosis, treatment sequencing and management. We present a rare case of a synchronous oral cavity and lymphoproliferative malignancy in a middle-age man. Our patient presented with a primary oral cavity squamous cell carcinoma and was subsequently found to have a secondary lymphoproliferative malignancy (chronic lymphocytic leukaemia/small lymphocytic lymphoma). The challenge of staging and sequencing of treatment is discussed. In addition, this case highlights the importance of multidisciplinary consultation, designing a personalised treatment plan that is coincident with the standard of care for each malignancy, and close follow-up.
Keyphrases
  • squamous cell carcinoma
  • epstein barr virus
  • palliative care
  • healthcare
  • lymph node
  • single cell
  • diffuse large b cell lymphoma
  • combination therapy
  • radiation therapy
  • chronic pain
  • lymph node metastasis