Association of patient weight status with plasma surfactant protein D, a biomarker of alveolar epithelial injury, in children with acute respiratory failure.
Shan L WardMary K DahmerHeidi M WeeksAnil SapruMichael W QuasneyMartha A Q CurleyKathleen D LiuMichael A MatthayHeidi R FloriPublished in: Pediatric pulmonology (2020)
Obesity was associated with lower plasma SP-D levels on day 2 of ARF. This finding may be explained by altered ARF pathogenesis in obese individuals or a reduced incidence of ventilator-induced lung injury.
Keyphrases
- respiratory failure
- weight loss
- mechanical ventilation
- metabolic syndrome
- extracorporeal membrane oxygenation
- weight gain
- type diabetes
- bariatric surgery
- acute respiratory distress syndrome
- insulin resistance
- adipose tissue
- high glucose
- body mass index
- case report
- diabetic rats
- physical activity
- intensive care unit
- obese patients
- oxidative stress
- drug induced
- high fat diet induced
- amino acid