RNA Sequencing and Gene Ontology Analysis in Acute Invasive Fungal Sinusitis.

Abel P DavidPatricia A LoftusMatthew S RussellAndrew N GoldbergIvan H El-SayedTaha A JanLauren T Roland

Published in: American journal of rhinology & allergy (2022)

Transcriptional differences were noted between AIFS and control patients in sinonasal tissue samples. Future work is necessary to determine causes of the differential gene expressions between AIFS and control patients, specifically those who are immunosuppressed, or with preexisting non-invasive forms of fungal sinusitis, to guide treatment and prevention strategies.

Keyphrases

end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
peritoneal dialysis
prognostic factors
gene expression
genome wide
copy number
single cell
oxidative stress
dna methylation
patient reported outcomes
current status
combination therapy
genome wide analysis