The glycosyltransferase ST3GAL2 is regulated by miR-615-3p in the intestinal tract of Campylobacter jejuni infected mice.

De XiLukas HofmannThomas AlterRalf EinspanierStefan BereswillMarkus M HeimesaatGreta GölzSoroush Sharbati

Published in: Gut pathogens (2021)

We report here for the first time the regulation of glycosyltransferases by miRNAs during murine infection with C. jejuni 81-176. Our data suggest that mucin type O-glycan biosynthesis is concerted by the interplay of miRNAs and glycosyltransferases, which could determine the shape of intestinal glycosylated proteins during infection.

Keyphrases

electronic health record
type diabetes
high fat diet induced
biofilm formation
adipose tissue
skeletal muscle
insulin resistance
data analysis
cell surface