Fluoroquinolone-Induced Photosensitivity: A Chemical Fragment-Based Approach by a Case/Non-case Study in VigiBase®.

Yoann ZelmatVanessa RousseauLeila ChebaneJean-Louis MontastrucHaleh BagheriAgnès Sommet

Published in: Drug safety (2021)

This study confirms the high reporting rate of photosensitivity adverse effects for sparfloxacin from real-world data. Moreover, our data suggest more photosensitivity adverse effects reporting for fluoroquinolones with a halogen at their 8th position.

Keyphrases

electronic health record
adverse drug
big data
high glucose
diabetic rats
machine learning
oxidative stress