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DNA methylation profile of genes related to immune response in generalized periodontitis.

Andrea Mara AzevedoLuiz Paulo Carvalho RochaSimone Angélica de Faria AmorminoCarolina Cavaliéri GomesWalderez Ornelas DutraHélder Antônio Rebelo PontesJosé Eustáquio da CostaPaula Rocha Moreira
Published in: Journal of periodontal research (2020)
Generalized periodontitis is associated with hypomethylation of the STAT5 gene. Further studies are necessary to evaluate the functional impact these findings.
Keyphrases
  • genome wide
  • dna methylation
  • immune response
  • genome wide identification
  • copy number
  • gene expression
  • cell proliferation
  • dendritic cells
  • toll like receptor
  • transcription factor
  • inflammatory response
  • drug induced