Coronary heart disease and risk for cognitive impairment or dementia: Systematic review and meta-analysis.
Kay DeckersSyenna H J SchievinkMaria M F RodriquezRobert J van OostenbruggeMartin P J van BoxtelFrans R J VerheySebastian KöhlerPublished in: PloS one (2017)
This meta-analysis suggests that coronary heart disease is prospectively associated with increased odds of developing cognitive impairment or dementia. Given the projected worldwide increase in the number of people affected by coronary heart disease and dementia, insight into causal mechanisms or common pathways underlying the heart-brain connection is needed.