Login / Signup

PNPLA3 148M/M Is More Susceptible to Palmitic Acid-Induced Endoplasmic Reticulum Stress-Associated Apoptosis in HepG2 Cells.

Yunzhi ChenXuemei YanTian WangHongrong DengXiaojie DengFen XuHua Liang
Published in: International journal of endocrinology (2023)
PNPLA3 148M/M cells were more susceptible to PA-induced lipid deposition and ER stress-related apoptosis than 148I/I cells, and the proapoptotic susceptibility of PNPLA3 148M/M is independent of LPC.
Keyphrases
  • endoplasmic reticulum stress
  • induced apoptosis
  • cell cycle arrest
  • oxidative stress
  • cell death
  • pi k akt
  • diabetic rats
  • high glucose
  • cell proliferation
  • endothelial cells