Minipool testing for SARS-CoV-2 RNA in United States blood donors.

Sonia Bakkour Coco Paula SaáJamel A GrovesLeilani MontalvoClara Di GermanioSonja M BestEduard GrebeKristin LivezeyJeffrey M LinnenDonna StraussDebra KesslerMark BonnValerie GreenPhillip WilliamsonSteve KleinmanSusan L StramerMars StoneMichael P Buschnull null

Published in: Transfusion (2021)

Blood donation MP-nucleic acid testing (NAT) indicated that SARS-CoV-2 RNAemia is infrequent and, when detected, the vRNA was at low concentrations. Only one RNA-reactive MP could be tested for infectivity for operational reasons and was not infectious in cell culture. These findings support current recommendations from international and national regulatory agencies to not screen donors by NAT.

Keyphrases

nucleic acid
sars cov
respiratory syndrome coronavirus
transcription factor
quality improvement