Foxp1 is Required for Renal Intercalated Dell Differentiation and Acid-Base Regulation.

Shi-Ting Wu Yu Feng Renhua Song Yanmiao Qi Lin LiDongbo LuYixuan Wang Wenrun Wu Angela T Morgan Xiaohong Wang Yin XiaRenjing LiuStephen I Alexander Justin Jong-Leong Wong Yuzhen Zhang Xiangjian Zheng

Published in: Journal of the American Society of Nephrology : JASN (2024)

Foxp1 is required for the renal intercalated cell differentiation and participated in acid-base regulation. Foxp1 regulated downstream transcriptional factors, Dmrt2 and Hmx2, which involved in the specification of distinct subsets of intercalated cells.

Keyphrases

regulatory t cells
induced apoptosis
transcription factor
dendritic cells
cell cycle arrest
gene expression
oxidative stress
signaling pathway
cell proliferation