The Associations of Selenoprotein Genetic Variants with the Risks of Colorectal Adenoma and Colorectal Cancer: Case-Control Studies in Irish and Czech Populations.

Maryam Mukhtar Niall AshfieldLudmila VodickovaVeronika VymetalkovaMiroslav LevyVáclav LiskaJan BruhaPetra BendovaJacintha O'SullivanGlen DohertyKieran SheahanBlathnaid NolanPavel VodickaDavid J Hughes

Published in: Nutrients (2022)

Several SNPs previously associated with CRC risk were also associated with CRC or colorectal neoplasia development in either the Irish or Czech cohorts. Selenoprotein gene variation may modify CRC risk across diverse European populations, although the specific variants may differ.

Keyphrases

case control
copy number
gene expression
primary care
human health
genetic diversity
climate change
genome wide identification
genome wide analysis