Combined ROS Responsive Polydopamine-Coated Berberine Nanoparticles Effective Against Ulcerative Colitis in Mouse Model.

Chenqi ChangHeng LiuXiaotong LiDandan SongYue LiuChang LuYu ZhenYing ChenJinguo XuWeidong LiXiaobin JiaZhipeng ChenRui Chen

Published in: International journal of nanomedicine (2024)

PDA@BBR NPs are ROS-responsive nanoparticles that adhere well and have a high drug loading capacity. They have shown therapeutic effects in mice with UC, indicating that this formulation may be a promising treatment option.

Keyphrases

mouse model
ulcerative colitis
cell death
dna damage
cancer therapy
reactive oxygen species
drug delivery
emergency department
combination therapy
skeletal muscle
magnetic nanoparticles
wild type