Plasma Methylated DNA Markers for Melanoma Surveillance.
Calise K BergerWilliam R TaylorDouglas W MahoneyKelli N BurgerKaren A DoeringAnna M GonserXiaoming CaoJustin HeilbergerBrianna J GysbersPatrick H FooteLisa A KottschadeSvetomir N MarkovicJulia S LehmanViatcheslav E KaterovHatim T AllawiJohn B KisielAlexander MevesPublished in: JCO precision oncology (2023)
MDMs identified by RRBS demonstrate a high degree of concordance with imaging results in the plasma of patients with metastatic melanoma. Further prospective studies in larger intended use cohorts are needed to confirm these findings.