Mendelian Randomization Analysis of Hemoglobin A1c as a Risk Factor for Coronary Artery Disease.
Aaron LeongJi ChenEleanor WheelerMarie-France HivertChing-Ti LiuRuth J F LoosJosée DupuisE Shyong TaiJerome I RotterJose C FlorezInês A BarrosoJames B MeigsPublished in: Diabetes care (2019)
Genetic evidence supports a causal link between higher A1C and higher CAD risk. This relationship is driven not only by glycemic but also by erythrocytic, glycemia-independent factors.