The effect of Pseudomonas aeruginosa eradication regimens on chronic colonization and clinical outcomes in pediatric patients with cystic fibrosis.
Halime Nayir BuyuksahinEbru YalçınNagehan EmiralioğluGulsen HazırolanDilber Ademhan TuralBeste ÖzsezenBirce SunmanIsmail GuzelkasDeniz DogruUgur OzcelikNural KiperPublished in: Pediatrics international : official journal of the Japan Pediatric Society (2022)
There was no difference between eradication regimens in delaying the age at Pa-CC. Pseudomonas aeruginosa colonization in patients with CF was also associated with poorer lung functions, lower body mass index, and more pulmonary exacerbation regardless of mucoid type. Consequently, to slow the progression of lung disease, we must prevent Pa-CC, which we can achieve with early eradication. Despite conventional eradication protocols, future studies need to evaluate those who fail to clear P. aeruginosa.
Keyphrases
- pseudomonas aeruginosa
- helicobacter pylori infection
- cystic fibrosis
- biofilm formation
- chronic obstructive pulmonary disease
- helicobacter pylori
- pulmonary hypertension
- acinetobacter baumannii
- escherichia coli
- current status
- staphylococcus aureus
- intensive care unit
- drug resistant
- acute respiratory distress syndrome
- extracorporeal membrane oxygenation