Splice-disrupt genomic variants in prostate cancer.

Ibrahim O AlanaziSalman F AlameryEsmaeil Ebrahimie Manijeh Mohammadi-Dehcheshmeh

Published in: Molecular biology reports (2022)

This is the first study that profiles the splice-disrupt genomic variants and their target genes in different types of prostate cancer. Unravelling alternative splicing opens a new avenue towards the establishment of new diagnostic and prognostic markers for prostate cancer progression and metastasis.

Keyphrases

prostate cancer
copy number
radical prostatectomy
genome wide
gene expression
transcription factor