Validation of a multi-ancestry polygenic risk score and age-specific risks of prostate cancer: A meta-analysis within diverse populations.

Fei ChenBurcu F DarstRavi K MadduriAlex A RodriguezXin ShengChristopher T RentschCaroline AndrewsWei TangAdam S KibelAnna PlymKelly ChoMohamed JallohSerigne Magueye GueyeLamine NiangOlufemi John OgunbiyiOlufemi PopoolaAkindele O AdebiyiOseremen I Aisuodionoe-ShadrachHafees O AjibolaMustapha A JamdaOlabode P OluwoleMaxwell NwegbuBen AduseiSunny ManteAfua O D AbrahamsJames E MensahAndrew Anthony AdjeiHalimatou DiopJoseph LachanceTimothy R RebbeckStefan AmbsJ Michael GazianoAmy C JusticeDavid V ContiChristopher A Haiman

Published in: eLife (2022)

This work was supported by the National Cancer Institute at the National Institutes of Health (grant numbers U19 CA214253 to C.A.H., U01 CA257328 to C.A.H., U19 CA148537 to C.A.H., R01 CA165862 to C.A.H., K99 CA246063 to B.F.D, and T32CA229110 to F.C), the Prostate Cancer Foundation (grants 21YOUN11 to B.F.D. and 20CHAS03 to C.A.H.), the Achievement Rewards for College Scientists Foundation Los Angeles Founder Chapter to B.F.D, and the Million Veteran Program-MVP017. This research has been conducted using the UK Biobank Resource under application number 42195. This research is based on data from the Million Veteran Program, Office of Research and Development, and the Veterans Health Administration. This publication does not represent the views of the Department of Veteran Affairs or the United States Government.

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