Semaphorin 7A coordinates Neutrophil response during pulmonary inflammation and sepsis.

Tiago Folgosa Granja David Köhler Linyan Tang Philipp BurkardClaudia EggsteinKatherina Hemmen Katrin G HeinzeKa-Lin Heck-SwainMichael KoeppenSven GüntherMaximilian Klaus BlahaHarry MaguniaMaximilian BambergFranziska Magdalena KonradKristian-Christos NgamsriAnika Fuhr Marius KellerAlice BernardHelene A HaeberleTamam BakchoulAlexander ZarbockBernhard NieswandtPeter Rosenberger

Published in: Blood advances (2024)

Sema7A has an immunomodulatory effect in the lung affecting pulmonary sepsis and ARDS. This effect influences the response of neutrophils to external aggression and might influence patient outcome.

Keyphrases

pulmonary hypertension
acute kidney injury
intensive care unit
septic shock
oxidative stress
acute respiratory distress syndrome
extracorporeal membrane oxygenation