Metabolic profiling of galectin-1 and galectin-3: a cross-sectional, multi-omics, association study.

Emanuel FrykVagner Ramon Rodrigues SilvaLena StrindbergRobin StrandHåkan AhlströmKarl MichaëlssonJoel KullbergLars LindPer-Anders Jansson

Published in: International journal of obesity (2005) (2024)

The association profiles for galectin-1 and galectin-3 indicate overlapping metabolic effects in humans, while the distinctly different associations seen with fat mass, fat distribution, and adipose tissue differentiation markers may suggest a functional role of galectin-1 in obesity.

Keyphrases

adipose tissue
insulin resistance
metabolic syndrome
type diabetes
high fat diet
physical activity
genome wide analysis