Trend of HIV transmitted drug resistance before and after implementation of HAART regimen restriction in the treatment of HIV-1 infected patients in southern Taiwan.
Ya-Wei WengI-Tzu ChenHung-Chin TsaiKuan-Sheng WuYu-Ting TsengCheng-Len SyJui-Kuang ChenSusan Shin-Jung LeeYao-Shen ChenPublished in: BMC infectious diseases (2019)
A fixed treatment regimen with zidovudine/lamivudine + efavirenz or nevirapine as first-line therapy for treatment-naïve patients infected with HIV did not significantly increase the TDR during the 4-year follow-up period. Due to the increase in NNRTI resistance associated with mutations after 2012, a longer follow-up period and larger sample size are needed in future studies.