PolyBoost: An enhanced genomic variant classifier using extreme gradient boosting.

Published in: Proteomics. Clinical applications (2021)

PolyBoost analyzes PolyPhen-2 output and can be incorporated into existing bioinformatics workflows as a post-analysis method to improve interpretation of clinical exome sequences obtained to identify monogenic disease.

Keyphrases

copy number
climate change
gene expression
dna methylation
genome wide