Heterozygous Genotype rs17580 AT (PiS) in SERPINA1 is Associated with COPD Secondary to Biomass-Burning and Tobacco Smoking: A Case-Control and Populational Study.
Gloria Pérez-RubioEnrique Ambrocio-OrtizLuis Alberto López-FloresAna I Juárez-MartínLuis Octavio Jiménez-ValverdeSusana Zoreque-CabreraGustavo Galicia-NegreteMaría Elena Ramírez-DíazFiliberto Cruz-VicenteManuel de Jesús Castillejos-LópezCitlaltepetl Salinas-LaraRafael de Jesús Hernández-ZentenoAlejandra Ramírez-VenegasRamcés Falfan-ValenciaPublished in: International journal of chronic obstructive pulmonary disease (2020)
The rs17580, AT genotype, is associated with COPD in Mexican-Mestizo smokers and exposed to biomass-burning smoke. The rs17580 AT is more frequent in the Mexican-Mestizo population of the North of the country, which has a high Caucasian component.