Proteomic analysis of decellularized mice liver and kidney extracellular matrices.
Anna-Maria DiedrichAssal DaneshgarPeter TangOliver KleinAnnika MohrOlachi A OnwuegbuchulamSabine von RuedenKerstin MenckAnnalen BleckmannMazen A JuratliFelix BeckerIgor M SauerKarl H HillebrandtAndreas PascherBenjamin StrueckerPublished in: Journal of biological engineering (2024)
The identification of distinct proteomic signatures provides insights into how different matrisome compositions might influence the biological properties of distinct tissues. This experimental workflow will help to further elucidate the proteomic landscape of decellularized extracellular matrix scaffolds of mice in order to decipher complex cell-matrix interactions and their contribution to a tissue-specific microenvironment.