Abdominal Ischemia-Reperfusion Induced Cardiac Dysfunction Can Be Prevented by MitoTEMPO.

Ahmet Akkoca Murat Cenk Celen Seckin Tuncer Nizamettin Dalkilic

Published in: Journal of investigative surgery : the official journal of the Academy of Surgical Research (2021)

Consequently, calcium homeostasis seems to be impaired by AIR, and MitoTEMPO may exert its protective effect through energy metabolism by directly targeting the mitochondria.

Keyphrases

high glucose
diabetic rats
oxidative stress
left ventricular
cell death
drug induced
reactive oxygen species
heart failure
endothelial cells
endoplasmic reticulum