Identification and genetic analysis of rare variants in myosin family genes in 412 Han Chinese congenital heart disease patients.

Yunqian ZhangRui PengHong-Yan Wang

Published in: Molecular genetics & genomic medicine (2022)

Overall, our findings suggest that MYL2 p.Ile158Thr and p.Val146Met contribute to the etiology of CHD. The results also indicate the importance of MYL2 in heart formation.

Keyphrases

congenital heart disease
end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
prognostic factors
bioinformatics analysis
binding protein
copy number
atrial fibrillation
transcription factor
dna methylation
genome wide identification