The safety of activated eptacog beta in the management of bleeding episodes and perioperative haemostasis in adult and paediatric haemophilia patients with inhibitors.
Miguel A EscobarGiancarlo CastamanSantiago Bonanad BoixMichael CallaghanPhilippe de MoerlooseJonathan DucoreCédric HermansJanna JourneycakeCindy LeissingerJames LuckJohnny N MahlanguWolfgang MiesbachIsmail Haroon MithaClaude G NegrierDoris QuonMichael RechtJean François SchvedAmy D ShapiroRobert SidonioAlok SrivastavaOleksandra StasyshynKateryna V VilchevskaMichael WangGuy Aaron YoungW Allan AlexanderAhmad Al-SabbaghDaniel BonzoChristopher MacieThomas A WilkinsonCraig KesslerPublished in: Haemophilia : the official journal of the World Federation of Hemophilia (2021)
Results from all three Phase 3 trials establish an excellent safety profile of EB in haemophilia A or B patients with inhibitors for treatment of bleeding and perioperative use.