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Phase II Study to Determine the Antitumor Activity and Safety of Simlukafusp Alfa (FAP-IL2v) Combined with Atezolizumab in Esophageal Cancer.

Hans PrenenSanjeev DevaBhumsuk KeamColin R LindsayIwona LugowskaJames Chih-Hsin YangFederico LongoMaria J de Miguel LukenMariano Ponz-SarviséMyung-Ju AhnMahmut GümüşStephane ChampiatAntoine ItalianoSebastien SalasRuth PeretsCagatay ArslanByoung Chul ChoStefan EversChristophe BoetschDaniel MarbachDavid DejardinNassim SleimanCaroline ArdeshirMuriel RichardJehad CharoAnton KraxnerNino KeshelavaVolker TeichgräberVictor Moreno
Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
FAP-IL2v plus atezolizumab demonstrated clinical activity and was tolerable in patients with previously treated esophageal SCC.
Keyphrases
  • phase ii study
  • open label
  • locally advanced
  • squamous cell carcinoma
  • radiation therapy
  • replacement therapy
  • placebo controlled